Amino acids in combination with other nutrients improve male infertility


Spermatozoons and ovule

For decades, male infertility has been contributing to shrinking birth rates in western countries. Approximately 10 to 17 percent of couples have primary or secondary sub-fertility issues, making conceiving difficult. 

Between 25 and 30 percent of all infertility causes relate to male factor. The specific cause of sub-fertility is difficult to diagnose and in almost half of all cases it remains undetermined.

A team of researchers from Austria reviewed various infertility studies conducted over the past 20 years investigating the link between micronutrients and male sub-fertility. Micronutrients are necessary for sperm cell metabolism, anti-oxidant protection of the precious DNA cargo, DNA synthesis during spermatogenesis and proliferation, i.e. sperm cell production.

PROfertil study

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Following on from the literature review, researchers also performed their own pilot study over four years at the outpatient Fertility Center IMI in Vienna, Austria. This study investigated the effects of moderate doses of vitamins, amino acids, essential fatty acids, coenzymes, vitaminoids and trace elements.

Ingredients that are proven to enhance sperm factors were formulated into a dietary supplement called PROfertil. These capsules contain:


L-carnitine 440 mg
L-arginine 250 mg
Coenzyme Q10 15 mg
Vitamin E 120 mg
Zinc 40 mg
Folic acid 800 mcg
Glutathione 80 mg
Selenium 60 mcg


A total of 132 men with impaired fertility received the micronutrient supplement for a period of three months. As a control, a group 73 sub-fertile men were given a placebo.

Participants that took the combination of micronutrients showed significant fertility improvements:

The Findings

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  • Improved sperm motility by 23 percent
  • An increase in total volume of ejaculate by 33 percent
  • An increase sperm cell density by as much as 215 percent


All values ​​represented a significant improvement in fertility in comparison with the control group. Within six months of completing the study, a total of 34 pregnancies were reported associated with men who took the micronutrient supplement.

fertilsan-MConversely, only eleven couples associated with the control group conceived within six months after the study.

In addition to PROfertil, there are several other suitable micronutrient supplements on the market that can help to enhance male fertility. Fertilovit Orthomol fertil plus and amitamin fertilsan M are two good options. amitamin fertilsan M also contains Carnipure, vitamin C and D, beta carotene, and N-acetyl-L-cysteine.

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